Dendritics公司主要关注人类树突状细胞，希望找到能够促使CD34+造血前体细胞转化为树突状细胞（在GM-CSF和TNF-alpha存在的情况下）的细胞因子。在1992-2005年间，大量的研究使得研究者对人类树突状细胞的产生、细胞通路、C-type凝集素受体的功能及Toll-like受体的活性有了更深的理解。

DENDRITICS was started in 2005 by former members of SCHERING PLOUGH Laboratory for Immunological Research (LIR) in Dardilly, France. From their long experience at LIR, the team members of DENDRITICS have gathered complementary scientific and technological knowledge in different areas of immunology. The initial focus of LIR was in the biology of B lymphocytes, elaboration of human monoclonal antibodies, and in cytokine discovery (IL-3, IL-4, IL-7, IL-10, IL-17, GM-CSF) together with our colleagues of DNAX Research Institute in Palo Alto, California.

Our interest in cytokines led to the finding that human dendritic cells (DCs) could be generated in vitro from CD34+ hematopoietic progenitors cultured in the presence of GM-CSF and TNF-alpha.

The period from 1992 to 2005 saw the specialization of LIR in DC biology and was fuelled by a large-scale effort to discover and study the function of genes specifically expressed by these cells. This program led to a number of findings that contributed in particular to understanding the heterogeneity of DCs, the pathways regulating DC migration, the function of C-type lectin receptors in DCs and the activity of Toll-like receptors in DCs. Many novel genes were discovered through screening of cDNA libraries or through monoclonal antibodies raised against DCs.

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艾美捷科技有限公司

全国服务热线：400-6800-868

邮箱：sales@amyjet.com

网站：www.amyjet.com

Dianova公司为德国著名的病理免疫组化产品供应商，具备领先的抗体制备工艺及严格的质控系统，产品在国际上享有良好的声誉。

Since its foundation in 1982, dianova GmbH provides professionals in Life Sciences with antibodies, immunoassays, and products for molecular biology. More than 30 years of grown expertise give rise to a fundamental knowledge about biochemical applications and a profound understanding of customer needs in research and routine diagnostic laboratories of universities, hospitals and the pharmaceutical industry.

Dianova公司的主要产品包括：

Proteine

Assays / Kits

Reagenzien / Medien

Material

Geräte

Antikörper-Service

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艾美捷科技有限公司

全国服务热线：400-6800-868

邮箱：sales@amyjet.com

网站：www.amyjet.com

Boston Biochem隶属于R&D System公司，是全世界最大的泛素相关产品的供应商。Boston Biochem生产的泛素产品包括蛋白、多肽、底物、小分子抑制剂、酶、蛋白酶体试剂盒交联试剂等。

Boston Biochem的主要产品包括：

Affinity Matrices / Proteins

Antibodies

Autophagy

Buffers

Deconjugating Enzymes

Deubiquitinating (DUBs)

E1 Activating

E2 Conjugating

E3 Ligase

Fractions

Heat Shock Proteins

Inhibitors

Kits

NEDD8

Other Ubiquitin-like

Proteasome

Substrate Proteins

SUMO & SUMOlyation

Ubiquitin